×
Entrez Id:
761
Gene Symbol:
CA3
CA3
Chemically-Induced Liver Toxicity
0.500
Biomarker
CTD_human
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model.
25231249
2015
×
Entrez Id:
5243
Gene Symbol:
ABCB1
ABCB1
Chemically-Induced Liver Toxicity
0.500
Biomarker
CTD_human
Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood.
20623750
2011
×
Entrez Id:
6652
Gene Symbol:
SORD
SORD
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Induction of hepatic heme oxygenase-1 by diclofenac in rodents: role of oxidative stress and cytochrome P-450 activity.
12763371
2003
×
Entrez Id:
100422867
Gene Symbol:
MIR378C
MIR378C
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
"Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human."
28545106
2017
×
Entrez Id:
574030
Gene Symbol:
MIR362
MIR362
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
"Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human."
28545106
2017
×
Entrez Id:
1356
Gene Symbol:
CP
CP
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Characterization of chemically induced liver injuries using gene co-expression modules.
25226513
2014
×
Entrez Id:
2936
Gene Symbol:
GSR
GSR
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Editor's Highlight: Transgenic Zebrafish Reporter Lines as Alternative In Vivo Organ Toxicity Models.
28069987
2017
×
Entrez Id:
406920
Gene Symbol:
MIR130B
MIR130B
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
"Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human."
28545106
2017
×
Entrez Id:
9970
Gene Symbol:
NR1I3
NR1I3
Chemically-Induced Liver Toxicity
0.300
Therapeutic
CTD_human
Hepatotoxic effects of cyproconazole and prochloraz in wild-type and hCAR/hPXR mice.
28058446
2017
×
Entrez Id:
2936
Gene Symbol:
GSR
GSR
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Characterization of chemically induced liver injuries using gene co-expression modules.
25226513
2014
×
Entrez Id:
8407
Gene Symbol:
TAGLN2
TAGLN2
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Characterization of chemically induced liver injuries using gene co-expression modules.
25226513
2014
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
Chemically-Induced Liver Toxicity
0.300
Therapeutic
CTD_human
Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood.
20623750
2011
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Amiodarone exposure during modest inflammation induces idiosyncrasy-like liver injury in rats: role of tumor necrosis factor-alpha.
21984482
2012
×
Entrez Id:
383
Gene Symbol:
ARG1
ARG1
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
A performance evaluation of three drug-induced liver injury biomarkers in the rat: alpha-glutathione S-transferase, arginase 1, and 4-hydroxyphenyl-pyruvate dioxygenase.
22872058
2012
×
Entrez Id:
9370
Gene Symbol:
ADIPOQ
ADIPOQ
Chemically-Induced Liver Toxicity
0.300
Therapeutic
CTD_human
Adiponectin-mediated heme oxygenase-1 induction protects against iron-induced liver injury via a PPARα dependent mechanism.
20709802
2010
×
Entrez Id:
4189
Gene Symbol:
DNAJB9
DNAJB9
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices.
26881866
2016
×
Entrez Id:
60
Gene Symbol:
ACTB
ACTB
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model.
25231249
2015
×
Entrez Id:
7100
Gene Symbol:
TLR5
TLR5
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
TLR5 silencing reduced hyperammonaemia-induced liver injury by inhibiting oxidative stress and inflammation responses via inactivating NF-κB and MAPK signals.
30508503
2019
×
Entrez Id:
9446
Gene Symbol:
GSTO1
GSTO1
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model.
25231249
2015
×
Entrez Id:
3553
Gene Symbol:
IL1B
IL1B
Chemically-Induced Liver Toxicity
0.300
Therapeutic
CTD_human
Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome.
19164858
2009
×
Entrez Id:
3565
Gene Symbol:
IL4
IL4
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Involvement of Th2 cytokines in the mouse model of flutamide-induced acute liver injury.
21735453
2012
×
Entrez Id:
1571
Gene Symbol:
CYP2E1
CYP2E1
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis.
16770646
2006
×
Entrez Id:
4057
Gene Symbol:
LTF
LTF
Chemically-Induced Liver Toxicity
0.300
Therapeutic
CTD_human
Liposomalization of lactoferrin enhanced it's anti-inflammatory effects via oral administration.
16141546
2005
×
Entrez Id:
5580
Gene Symbol:
PRKCD
PRKCD
Chemically-Induced Liver Toxicity
0.300
Therapeutic
CTD_human
Protein kinase Cδ knockout mice are protected from cocaine-induced hepatotoxicity.
30393195
2019
×
Entrez Id:
2950
Gene Symbol:
GSTP1
GSTP1
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood.
20623750
2011